Experimental Alzheimer’s drug found to trigger fat burning without diet
The enzyme inhibitors developed by Pfizer and tested as a potential treatment of Alzheimer’s is the subject of the new study, but has nothing to do with memory. Instead, the researchers found that inhibiting the enzyme called PDE9 caused mice overweight to burn a large number of fats without changes to their diet and activity levels … even though there was a very large catch.
New studies, must be recorded, involves mice, not humans, and additional research in humans will be needed to determine whether a similar product can be developed to treat obesity in people. In this case, this study involves male mice and females; Some female rats have their ovaries released while others remain intact.
This study, which comes from Johns Hopkins University, involves lab mice for eating a high-fat diet; After four months of eating it, mice doubled their weight besides developing diabetes and high blood lipid levels. Some mice also have pressure pressure on the heart intended to mimic the effect of cardiometabolic syndrome.
Some mice were given placebo while other mice were given an enzyme inhibitor of PDE9. While this drug was finally not proven to be a useful treatment of Alzheimer’s, the researchers found that indeed it did lead to weight loss that could be recorded in mice without reducing their slim body mass or needed a change in diet / activity.
Male rats have changed in an average weight of 19.5 percent while female rats experienced a reduction of 27.5 percent. However, the catch is that only female mice without ovaries have changed in a well-known weight, while female rats that still have ovaries do not experience the same changes. The researchers said this showed the role of estrogen in severe regulations.
The findings someday pave the way for treatments that help women spill the central weight that is usually obtained during menopause. Assuming the same effect can be translated from mice to humans, the researchers estimate that 250LB humans will lose around 50LBs to take this kind of enzyme inhibitor without changes in exercise or diet.
Leave a Reply